{"id":1404,"date":"2015-01-24T16:46:30","date_gmt":"2015-01-24T16:46:30","guid":{"rendered":"http:\/\/castoroil.in\/b\/?p=1404"},"modified":"2015-01-24T16:46:30","modified_gmt":"2015-01-24T16:46:30","slug":"genetic-engineering-methods-to-overcome-toxicity-challenges-in-castor-industry","status":"publish","type":"post","link":"http:\/\/castoroil.in\/b\/2015\/01\/genetic-engineering-methods-to-overcome-toxicity-challenges-in-castor-industry\/","title":{"rendered":"Genetic Engineering Methods to Overcome Toxicity Challenges in Castor Industry"},"content":{"rendered":"<p>The toxicity of castor, in the form of ricin, is one of the key challenges that is slowing the adoption of castor as a crop in some countries, especially in the developed parts.<\/p>\n<p>Toxicity challenges in castor industry can be overcome through genetic engineering.<\/p>\n<p>An example of this is the Genetic Engineering of <em>Lesquerella fendleri<\/em> for castor oil production.<\/p>\n<ul>\n<li>Seed oil of Lesquerella fendleri (Lf) contains a valuable hydroxy fatty acid (HFA), lesquerolic acid (20:1OH).<\/li>\n<li>Lf does not have biological toxic compounds, thus its oil represents an alternative source of HFA. Lesquerolic acid is derived by a 2 carbon elongation of 18:1OH.<\/li>\n<li>By suppressing the elongation step through genetic engineering, it is possible to generate a new Lf crop that could produce 18:1OH.<\/li>\n<\/ul>\n<p>Novo Synthetix, USA has followed the genetic engineering technique in castor such that it no longer produces ricin. No new DNA is introduced, mainly tweaking of genes.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>The toxicity of castor, in the form of ricin, is one of the key challenges that is slowing the adoption of castor as a crop in some countries, especially in the developed parts. Toxicity challenges in castor industry can be &hellip; <a href=\"http:\/\/castoroil.in\/b\/2015\/01\/genetic-engineering-methods-to-overcome-toxicity-challenges-in-castor-industry\/\">Continue reading <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[26,25],"tags":[78,158,157,159],"class_list":["post-1404","post","type-post","status-publish","format-standard","hentry","category-castor-research","category-castor-toxin","tag-castor-toxicity","tag-genetic-engineering-castor","tag-gm-castor","tag-ricin"],"_links":{"self":[{"href":"http:\/\/castoroil.in\/b\/wp-json\/wp\/v2\/posts\/1404","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/castoroil.in\/b\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/castoroil.in\/b\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/castoroil.in\/b\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/castoroil.in\/b\/wp-json\/wp\/v2\/comments?post=1404"}],"version-history":[{"count":2,"href":"http:\/\/castoroil.in\/b\/wp-json\/wp\/v2\/posts\/1404\/revisions"}],"predecessor-version":[{"id":1407,"href":"http:\/\/castoroil.in\/b\/wp-json\/wp\/v2\/posts\/1404\/revisions\/1407"}],"wp:attachment":[{"href":"http:\/\/castoroil.in\/b\/wp-json\/wp\/v2\/media?parent=1404"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/castoroil.in\/b\/wp-json\/wp\/v2\/categories?post=1404"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/castoroil.in\/b\/wp-json\/wp\/v2\/tags?post=1404"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}