Scientists from Brazil conducted an experiment to evaluate the biocompatibility and osteogenesis of castor oil polymer doped with SiO2 or BaTiO3 nanoparticles.
Twenty-four rats with bone defect were experimented with castor oil polymer doped with SiO2 or BaTiO3. Euthanasia occurred 30 and 60 days after surgery and the femurs were sent to histological analysis and MEV. Results showed that the implants were biocompatible and allowed for progressive osteogenesis. Thus, castor oil polymer doped with SiO2 or BaTiO3 remains biocompatible and allows for osteogenesis.