It is not astonishing to see the action of this oil from castor seed on administration of it as a remedy to gastro-intestinal disorders across humans of all the ages in the world. Even then mystery with castor oil has remained all throughout the ages over the way this edible laxative works in physical system to display conditions of stool emergency. With science as a tool for facts, researchers at a German centre, The Max Planck Institute for Heart and Lung Research finally have unraveled the mode by which castor oil expresses its functionality in the human body. Authours of the study report that it is exciting to watch that cells in intestine harbours a receptive protein called, EP3 that recognizes the ingested castor oil and mediates cells and their constituents to elicit the laxative effect. Following a robust experimental analysis in animal models to attribute the sensory factors of castor oil derived ricinoleic acid, scientific experts and critical analysts believe that there could be a modulation brought about in the human body to selectively harvest the therapeutic activities and avoiding irritating side effects from castor oil.
For reference: http://www.cosmosmagazine.com/news/5608/scientists-uncover-mechanism-behind-ancient-drug