In this study, preparation of novel antibacterial and cytocompatible polyurethane membranes for occlusive dressing, which can provide moist and sterile environment over mild exudative wounds is considered. An epoxy-terminated polyurethane (EPU) prepolymer based on castor oil and glycidyltriethylammonium chloride (GTEAC) as a reactive bactericidal agent were synthesized. Polyurethane membranes were prepared through cocuring of EPU and different content of GTEAC with 1,4-butane diamine. The physical and mechanical properties, as well as cytocompatibility and antibacterial performance of prepared membranes were studied. Read – http://onlinelibrary.wiley.com/doi/10.1002/jbm.a.34672/abstract