Undecylenic acid is an unsaturated fatty acid obtained from castor oil by pyrolysis of riccinoleic acid.
Undecylenic acid is mainly used for the production of Nylon-11 and in the treatment of fungal infections of the skin, but it is also a precursor in the manufacture of many pharmaceuticals, personal hygiene products, cosmetics, and perfumes.
Geographically, the Undecylenic Acid market dominance over North America, Latin America, Europe, Asia-Pacific, Middle East & Africa, North America held the majority of the Undecylenic Acid market share in 2017. Rest of the World is likely to have a limited but steady growth in the Undecylenic Acid market.
Global undecylenic market was worth over US$ 310 million in 2015 and is expected to reach more than US$ 520 million in 2023, growing at a CAGR of 5.8%.
Increasing pharmaceutical applications coupled with growing consumer awareness for biobased products is expected to drive the undecylenic acid market.
In the castor oil market, India dominated the castor oil production and accounts for over 60% of the total volume with over 900 kilo tons of capacity. China and Brazil account close to 20% & 10% respectively of the total production volume.
Global undecylenic acid market size was estimated at over 170 kilo tons in 2015 and is likely to exceed 240 kilo tons by 2023, growing at a CAGR of over 4.2%. This market is was worth over USD 310 million in 2015 and is likely to be valued more than USD 520 million by 2023, growing at a CAGR of over 5.8%.
FDA approval for medical applications is likely to favor undecylenic acid market growth over the forecast period. It is also used against candida infection and also relives irritation, itching and burning sensations on skin.
Here is an interesting article on the enhanced neuroprotective effects of undecylenic acid.
Undecylenic acid, a synthetic unsaturated fatty acid obtained from castor oil is a well-known potent antifungal agent. In 2012, scientists from Korea found that undecylenic acid has the ability to inhibit µ-Calpain activity, a factor responsible for neurological disorders like Alzheimer’s disease. This showed the neuroprotective effects of undecylenic acid.
Now scientists from Poland have done an experiment to improve the efficiency of neuroprotective effects of undecylenic acid by targeting it using polyelectrolyte coated nanocapsules. Core shell nanocapsules were prepared using nanoemulsification and the layer by layer technique. The average size of nanocapsules was around 80nm and the concentration was 2.5×1010 particles/ml. The nanocapsules were coated with either polycation or polyanion layers.
Biocompatibility of the synthesized nanocarriers was evaluated in SH-SY5Y human neuroblastoma cell line using cell viability/toxicity assays.
Results showed that nanocapsules coated with PLL and PGA were non-toxic to the human neuroblastoma cell line, thereby showing its potential to be used as a carrier of undecylenic acid. Further research showed that nanoencapsulated form of undecylenic acid was biocompatible and more effective against staurosporine-induced damage in lower concentrations than those of the same drug added directly to the culture medium.
This shows that undecylenic acid could be more effective in nanoencapsulated form against neurological disorders.
Wish to know more about undecylenic acid – see here